fig12

Zwitterionic hydrogels and their biomedical applications: a review

Figure 12. (A) zwitterionic polymer ZPS (PS-mimetic polymers): design scheme, fibrinogen adsorbed onto different hydrogel surfaces, the status of macrophage evaluated by measuring the production and release of TNF-α. Reproduced with permission from[184]. NS: No significance; *P < 0.05, ***P < 0.001. Data are represented as mean ± SEM. Copyright 2020, American Association for the Advancement of Science; (B) Non-immunogenic stealth microrobots prepared by CBMA and SBMA. Reproduced with permission from[186]. Copyright 2020, Wiley-VCH GmbH; (C) DS-loaded MGS@DMA-SBMA (superlubricated microspheres): schematic illustration, hydration lubrication and sustained drug release, COF-time curve, drug release profile. Reproduced with permission from[28]. Copyright 2020, Wiley-VCH GmbH. MPC: 2-Methacryloyloxyethyl phosphorylcholine; ZPS: zwitterionic phosphoserine-mimetic polymer; DS: diclofenac sodium; DMA: dopamine methacrylamide; SBMA: sulfobetaine methacrylate; CBMA: carboxybetaine methacrylate; COF: coefficient of friction.

Chemical Synthesis
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