fig2

Organocatalytic Nazarov-type cyclization of 3-alkynyl-2-indolylmethanols: construction of axially chiral cyclopenta[<i>b</i>]indole scaffolds

Figure 2. Substrate scope of Nazarov-type cyclization. Reaction conditions: 0.2 mmol scale; 10 mol% 4a; CHCl3 (1.0 mL); 30 ℃; 12 h; 1:2 = 1.5:1. Isolated yields.

Chemical Synthesis
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