fig16

Figure 16. Photothermal enhanced chemotherapy: (A) The synthetic protocol of the Cu₉S₅@mSiO₂-PEG^[150]; (B) Illustration of the tumor-specific in situ transition chelating reaction and augmentation generated by photothermal effect under NIR laser irradiation; (C) Chemo-photothermal synergistic therapy: Schematic Illustration of Fabrication and Bioapplication of CFPP NPs and (D) and (E) Photothermal images (F) PAI of CFPP NPs at different times after intravenous injection; (G) MRI of CFPP NPs. (H) MRI in vivo (I) PAI of CFPP NPs at different concertation of CFPP and (J) PAI in vivo^[138]. (A)-(B): Copyright © Wiley-VCH 2013; (C)-(J): Copyright © American Chemical Society 2022. MRI: magnetic resonance imaging; PAI: photoacoustic imaging.