fig2

Acyl transfer-enabled catalytic asymmetric Michael addition of <i>α</i>-hydroxy-1-indanones to nitroolefins

Figure 2. The calculated free energy profile and geometries of the key transition states for the enantioselectivity-determining Michael addition step (calculations were performed at the M06/6-311++G(d,p)/SDD//B3LYP-D3BJ/6-31G(d,p)/LANL2DZ//SMD(solvent=Acetonitrile) level of theory; bond distances are given in Å).

Chemical Synthesis
ISSN 2769-5247 (Online)

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