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Chem Synth 2021;1:[Accepted].10.20517/cs.2021.07@The Author(s) 2021
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Recent advances on radical phosphorylation (2016-up till now)

Correspondence Address: Dr. Qiang Fu, Department of medicinal chemistry, School of Pharmacy, Southwest Medical University, No.319 Section 3, Zhongshan Road, Luzhou 646000, Sichuan, China. E-mail: fuqiang@swmu.edu.cn, ORCID: 0000-0001-9993-8776; Dr. Da-Gang Yu, Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, No.24 South Section 1, Yihuan Road, Chengdu 610064, Sichuan, China. E-mail: dgyu@scu.edu.cn; ORCID: 0000-0001-5888-1494


© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.


Organophosphorus compounds are of great significance in organic chemistry. Therefore, the construction of phosphorus-containing compounds has attracted much attention of organic chemists. Radical phosphorylation has become a powerful strategy to build organophosphorus compounds, and great achievements has been obtained in the past several years. In this review, we summarize the development on the generation and application of phosphorus radical in organic chemistry since 2016. Special emphasis is put on various new transformations involving the generation of P-centered radicals via transition metal-catalysis, photochemical, and electrochemical means. Recent advances on the development of metal-free catalytic phosphorylatations involving P-centered radicals are also reviewed.

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Liu J, Xiao HZ, Fu Q, Yu DG. Recent advances on radical phosphorylation (2016-up till now). Chem Synth 2021;1:[Accept]. http://dx.doi.org/10.20517/cs.2021.07

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